Addictive Potential of a Substance
The Schedule of Controlled Substances was established in 1970 and classified various substances for their addictive potential on a schedule of I to V with Schedule I representing the most addictive and V the least addictive. This formula used by the Food and Drug Administration and other governmental agencies is not based upon any scientific premise, although it has been widely utilized since 1970 and had a profound impact on policy as well as research of various substances with addictive potential.
Today it is with great joy that I share my discovery of an algebraic formula that expresses the addictive potential of any substance: A = E/Tmax x T1/2, where A represents the addictive potency, E is the euphoric potency on a scale of 0 to 10 with 10 representing the strongest and 0 the weakest, TMAX is the time necessary to reach the maximum plasma concentration and T1/2 is the plasma elimination half life.
The scientific logic and clinical evidence that led to my discovery will be published soon in a peer-reviewed journal, yet the importance of my discovery made me decide not to wait to share the formula with the public immediately. Animal studies and clinical evidence suggest that three factors i.e. the euphoric potency, the onset of action and the severity of withdrawal symptoms contribute to addictive properties of any substance (Weinberger DR (1995): Neurodevelopmental perspectives on Schizophrenia. In Psychopharmacology: The Fourth Generation of Progress (F.E. Bloom and D.J. Kupfer, Eds.), pp.1171-1183. Raven Press, New York).
All rights of the above formula are reserved. No one is permitted to use the Salerian Euphoric Equation without the written consent of Alen J. Salerian, MD, PC and Washington Center for Psychiatry.